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(주)녹십자웰빙
GC Arginine (Diet)
GC Arginine (Diet)
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$265.00 USD
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1) Efficacy and effect
1. In the case of acute exacerbation of hyperammonemia due to the following diseases and when control is not possible with oral administration, a decrease in ammonia concentration in the blood
1) Congenital urea circuit abnormality
- Carbamyl phosphate synthetase (CPS) deficiency
- Ornitine transcarbamylase (OTC) deficiency
- Arginosuccinate synthetase (ASS) deficiency
- Arginosuccinate lyase (ASL) deficiency
2) Lysinuric protein intolerance
2. Acidifying agent in severe metabolic alkalosis
3. Pituitary function test to measure growth hormone secretion
- Use instead of or together with the insulin-induced hypoglycemia test. Because it may result in a false positive or false negative, the diagnosis should not be made solely through a test using this drug.
2) Dosage, usage
1. In case of acute exacerbation of hyperammonemia, the concentration of ammonia in the blood decreases only when it cannot be controlled by oral administration.
- 0.2 to 1 g of L-arginine hydrochloride per kg of the patient's body weight is slowly injected intravenously over 1 hour.
2. Acidifying agent in severe metabolic alkalosis
- The intravenous injection dose is l-arginine hydrochloride = reduction in plasma carbonate concentration to be achieved (mM/L) × [patient's weight (kg) / 9.6]
3. Pituitary function test to measure growth hormone secretion
- 500 mg of L-arginine hydrochloride per kg of the subject's body weight as a 10% solution is injected intravenously slowly over 30 minutes.
- Diagnosis method
1) Diagnosis the next morning after fasting and sleeping as usual
2) Lie down and rest for at least 30 minutes before the injection.
3) After injection into the antecubital vein or other appropriate site, blood is collected from the vein of the opposite arm.
4) The blood collection schedule is divided into 30 minutes before, 0, 30, 60, 90, 120, and 150 minutes.
5) After starting the infusion, administer the recommended amount for 30 minutes without changing the dosage.
6) Blood collected before radioimmunoassay is immediately centrifuged and plasma is stored at -20°C.
7) The result of growth hormone deficiency is diagnosed by retesting this drug or an insulin-induced hypoglycemia test (recommended test interval is after waiting 1 day).
3) Ingredients, content
L-arginine hydrochloride 0.6g
4) Packaging unit
10mL, 25mL/vial x 10
5) Period of use
36 months from date of manufacture
6) How to save
Sealed container, stored at room temperature (1~30℃)
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